What is Spravato® ?
Spravato® (esketamine) is an FDA-approved nasal spray medication used for:
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Treatment-Resistant Depression (TRD) in adults
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Major Depressive Disorder (MDD) with acute suicidal ideation or behavior
Spravato works differently from traditional antidepressants. Instead of targeting serotonin, it acts on the NMDA receptor to rapidly improve communication within mood-regulating pathways in the brain. Many patients begin to feel improvement within hours to days rather than weeks.
At Anew Psychiatry, Spravato® is administered onsite in a safe, supportive environment under the supervision of trained clinical staff, in compliance with the REMS (Risk Evaluation and Mitigation Strategy) Program.
How Spravato® Works
Depression is linked to slowed or disrupted neural communication. Spravato® helps:
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Increase glutamate activity (a major excitatory neurotransmitter)
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Strengthen synaptic connections
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Restore communication between mood-regulating brain regions
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Promote long-term neuroplasticity
Spravato® is taken in combination with an oral antidepressant for best results.
Who is a Good Candidate?
Spravato® may be right for adults who:
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Have tried 2+ antidepressants without sufficient relief
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Need faster symptom improvement
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Are experiencing suicidal thoughts
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Prefer an evidence-based treatment that works differently from traditional medications
Your provider will complete a full evaluation to determine if Spravato® is appropriate for your specific needs.
Your Healing Starts Here
If depression has been holding you back even after trying multiple medications Spravato® may help you find meaningful relief.
Contact us today to schedule an evaluation and explore whether Spravato® is right for you.
What’s Included
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Why It Matters
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Our Approach
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Our Services
GeneSight® Test
Transcranial Magnetic Stimulation
SPRAVATO® (esketamine)
Anxiety
Mood Disorders
Sleep Disorders
General Psychiatry
Depression
ADHD
Our Insurance Affiliations
We work with many major insurance providers to ensure your visit is smooth and stress-free. Below are some of the plans we accept. Don’t see yours? Contact us, we’re here to help.